The sanctuary has provided food, shelter, medical care for more than 30 years to horses, donkeys and ponies, are staff are devastated with the situation.
A quantity of goods, merchandise and money was stolen from the animal sanctuary and the building was also subject to deliberate flooding leaving all of the taps on in the visitor centre toilets and the kitchen.
The sanctuary's beautiful wooden carving of a horse known as 'Milton' at the centre was stolen. The carving was given as a gift to the charity and it is hoped that he can be returned in one piece.
A spokesperson for Tayside Police said: "Tayside Police is investigating a break-in to Mountains Animal Sanctuary, Glen Ogil by Kirriemuir sometime between 9.30 p.m. on Sunday, December 9, and Monday, December 10. Thieves made off with a quantity of money, along with goods and merchandise from the visitors centre.
"Anyone with any information that may be useful should contact PC Alan Bell at Tayside Police on 0300 111 2222. Alternatively information can be passed anonymously via the charity Crimestoppers on 0800 555 111."
* For the full story see this week's issue of The Scottish Farmer, on sale on Friday, December 14 2012.